Molecular pathology and thyroid FNA
نویسندگان
چکیده
منابع مشابه
Molecular biomarkers in thyroid FNA samples.
In this issue of the JCEM, Walsh et al. (1) report the analytical validation of a molecular diagnostic method for indeterminate fine-needle aspiration (FNA) thyroid samples. Together with previous reports describing clinical performance and cost effectiveness of this method, this study highlights the capability of such a molecular test to reduce unnecessary surgery for benign thyroid diseases (...
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OBJECTIVES Medullary thyroid carcinoma (MTC) is a relatively uncommon type of thyroid malignancy, with unique histologic features and molecular pathology. It is important to recognize, because its management, which is in part driven by the genetic basis of this disease, is different from follicular-derived thyroid tumors. The aim of this article is to briefly review the histopathologic features...
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BACKGROUND Accurate preoperative assessment of thyroid nodules with fine-needle aspiration biopsy (FNAB) continues to be a challenge, often resulting in unnecessary diagnostic surgical intervention. The detection of several novel gene mutations in differentiated thyroid cancer (DTC) over the last decade has led to the diagnostic use of these oncogenic alterations to improve FNAB sensitivity and...
متن کاملOffice-Based Ultrasound-Guided FNA with Molecular Testing for Thyroid Nodules.
OBJECTIVE Ultrasound-guided fine-needle aspiration (FNA) biopsy is the primary method of evaluating thyroid nodules. Up to one-third of FNA results are reported to be of "indeterminate" cytology, which carries a 25% malignancy risk. Most of these patients are referred for diagnostic surgery, which results in many unnecessary interventions. We implemented an FNA protocol combining expert thyroid...
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Thyroid disorder is a general term representing several different diseases involving thyroid hormones and the thyroid gland. Thyroid disorders are commonly separated into two major categories, hyperthyroidism and hypothyroidism, depending on whether serum thyroid hormone levels (T4 and T3) are increased or decreased, respectively. Thyroid disease generally may be sub-classified based on etiolog...
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ژورنال
عنوان ژورنال: Cytopathology
سال: 2017
ISSN: 0956-5507
DOI: 10.1111/cyt.12492